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Most people find that taking these supplements in the morning on an empty stomach (about 20 minutes before eating) allows for the best absorption

High doses of Vitamin C taken within 1 hour of the shot may lower B12 in blood (minor, stagger doses)

For a researcher who wants to explore this combination in vitro or preclinically, it is precisely a good topic for original research, not an established fact

Int J Basic Clin Pharmacol

Redox signaling and the emerging therapeutic potential of thiol antioxidants