Both peptides have documented neuroprotective research activity: Epitalon demonstrated reduction of amyloid precursor protein (APP) processing markers in rodent brain models, improved behavioural performance in aged animals (Morris Water Maze, novel object recognition), and neuroprotective effects potentially mediated via melatonins anti-amyloidogenic and anti-tau hyperphosphorylation activity
Intestinal Anti-Inflammatory Activity (KPV): KPV (Lys-Pro-Val) is a tripeptide that research suggests can attenuate NF-kB signaling in intestinal epithelial cells, reducing pro-inflammatory cytokine expression relevant to colitis models
, The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: Results of a double-blind, placebo-controlled phase II trial, J
ECLIPSE Ni-U Upright Microscope (NIKON, Japan)
Water, Butylene Glycol, Glycerin, Dimethicone, Panthenol, Titanium Dioxide (CI 77891), Niacinamide (20,000ppm), Cyclopentasiloxane, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Polyacrylate, Isohexadecane, Ethylhexyl Stearate, Chlorphenesin, Phenoxyethanol, Dimethiconol, Polysorbate 80, Betaine, Caprylyl Glycol, Ethylhexylglycerin, Triethoxycaprylylsilane, Aluminum Hydroxide, Sorbitan Oleate, Fragrance, Trideceth-6, Pantalactone, Disodium EDTA, Terminalia Ferdinandiana Fruit Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Glutathione (10ppm), Citrus Tangerina (Tangerine) Extract, Hexyl Cinnamal, Benzyl Benzoate, Limonene
Overall, these observations suggest that Cyss uptake in TNBC can maintain NRF2 activation to promote substantial OS resistance, but also, less obviously, EMT and stem-like phenotype of MSL TNBC