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Increased permeability without severe mucosal damage is caused by tight junction protein abnormalities, whereas severe mucosal damage disrupts the barrier and causes uncontrolled leakage of the luminal contents
Available evidence suggests AHK-Cu is well tolerated with topical application
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That matters for anyone whose gut doesnt absorb B12 well, think pernicious anemia, celiac disease, or a history of gastric surgery
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