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Research has also described a distinct potency pattern across its receptor targets: This balanced profile provides a framework for studying coordinated metabolic responses rather than isolated single-pathway effects

In addition, DPP-4i can alleviate vascular inflammation in hypertension by regulating inflammatory responses and improving vascular endothelial function, thereby reducing the incidence of cardiovascular complications

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10.1007/s11357-016-9871-8 80 KimM

A simulated treatment comparison was used to assess percentage change from baseline in body weight