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The core protein has 191 amino acids and can be divided into three domains on the basis of hydrophobicity: domain 1 (residues 1117) contains mainly basic residues with two short hydrophobic regions

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HDAC3 has also been demonstrated to improve endothelial dysfunction in type 2 diabetes mellitus (T2DM)-associated cardiovascular disease by mitigating inflammation and oxidative stress

24 shows that improved recovery is very strongly associated with lower mortality ( p 0% increased risk from 3 studies

Additional information Peer review information Nature Reviews Gastroenterology & Hepatology thanks P