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GLP-1 medication use for type 2 diabetes has soared

Therefore, free carnitine availability can be a limiting factor in mitochondrial fatty-acid translocation both at rest and during low-intensity exercise, and an increase in skeletal muscle total carnitine content would increase the fatty-acid oxidation while reducing PDC activation and glycogen utilization during lowmoderate-intensity exercise [23]

Morbid obesity (as discussed above in the section on dosing)

PREGNANCY If pregnant, consult your health professional before using this product

PMID: 39325560

GLP-1 receptor agonists also have favourable effects on albuminuria and may slow eGFR decline , though the evidence for hard renal outcomes is less robust than for SGLT2 inhibitors