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An online vial is not automatically equivalent to historical trial material

PLoS One 18 , e0294355 (2023)

Excessive doses of glutathione, especially when given intravenously or by injections, can have unfavorable side effects such as gastrointestinal distress, allergic responses, and in rare instances, liver damage

Reducing agents such as DTT or beta-mercaptoethanol in assay buffers will disrupt the disulfide bridge and inactivate the peptide

Having failed enough times, they've just given up and consigned themselves to die heavy

Hohenfellner K, Niessl C, Haffner D, Oh J, Okorn C, Palm K, Schlingmann KP, Wygoda S, Gahl WA (2022) Beneficial effects of starting oral cysteamine treatment in the first 2 months of life on glomerular and tubular kidney function in infantile nephropathic cystinosis