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In another system, GSH cleaves tetrasulfide bonds in an organosilica shell to explosively release encapsulated liquid ion drugs (Na + S 2 O 8 2 )

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10 nmol/kg dose: PBS/PBS, n = 7

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For example, 2 g of compound resulted 1 / kg in a reaction of the penis after intravenous injection in rats, while 100 g melanotan-II / kg body weight for one appropriate reaction of the penis were required