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A novel KDM5A/MPC-1 signaling pathway promotes pancreatic cancer progression via redirecting mitochondrial pyruvate metabolism

Limited research on human subjects: While Dihexa has shown promise in preclinical studies and animal models, there is a scarcity of clinical research evaluating its safety and potential side effect in humans

KHA verified the underlying data

Furthermore, disease models based on the transgenic expression of ALS-associated mutations in vivo have been used extensively to investigate ALS pathogenesis and motor neuron degeneration (Taylor et al., 2016)

Bloomgarden et al reported results from a meta-regression analysis of 61 clinical trials evaluating the efficacy of the five major classes of oral anti-hyperglycemic agents (11)