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Abstract Background Intracellular hydroperoxides are harmful reactive oxygen species that can cause damage

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Initial Dose : Start with 50 mg (0.5 mL) subcutaneously once weekly for 4 weeks

MET activation is thus involved in brain plasticity, as suggested by the fact that HGF administration on hippocampal slices enhances the phosphorylation of the glutamatergic NMDA receptor subunit GluN1, augments the NMDA-mediated currents, and increases the amplitude of long-term potentiation (LTP) induced by elevated neuronal activity (Kato et al., 2012)