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86% of participants achieved a weight loss of 5% or more, validating semaglutide's effectiveness in enhancing weight loss when combined with lifestyle changes

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For individuals managing weight or blood glucose stability, this profile is significantly different from sucralose, aspartame, or stevia, which do not reliably stimulate GLP-1 secretion

With continued medication use, spontaneous resolution has been documented at four to six weeks and up to four months