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RNA from liver tissue was extracted using Trizol reagent (Invitrogen, Cergy Pontoise, France)

It mimics the action of naturally occurring GLP-1, a hormone released by the intestine in response to food intake

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Here is an incomplete list of medications commonly used by people with type 2 diabetes which list fatigue or tiredness as adverse reactions: Metformin: The most commonly used medication for type 2 diabetes can increase the risk of vitamin B12 deficiency, which can cause people to feel tired or weak

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First of all, it increases energy and focus