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Some synthetic progestins that may cause symptoms 6 include: Oral contraceptive pills Long-acting progestin injections Contraceptive vaginal rings Progestin-containing IUDs High-dose progesterone used in IVF treatments Certain corticosteroids, due to their similarity to progesterone If youve recently started taking contraceptives and are noticing changes in your skin, discuss alternatives with your provider, such as combination birth control pills, that may be able to help manage your symptoms better