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GLP-1 has also been found to increase mRNA and protein expression levels of AP2 and PPAR in a dose-dependent manner during pre-3T3-L1 adipocyte differentiation

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4.7 Appetite and satiety Appetite and weight regulation are controlled by the central nervous system in a fairly complex manner, with the human brain playing a central role in integrating internal and external inputs and regulating energy homeostasis (Farr et al., 2016a)