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For now, the available data supports both approaches

The only practical research format is a lyophilized (freeze-dried) powder reconstituted with bacteriostatic water and injected subcutaneously or intramuscularly

instead, it indirectly affects NAD+ by inhibiting an enzyme called NNMT (nicotinamide N-methyltransferase)

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However, B12 shots are less likely to increase energy or performance when B12 levels are already normal

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