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Acknowledgements This study was in part supported by Lonza (Basel, Switzerland)

Celecoxib, a highly selective COX-2 inhibitor, has been shown to suppress neuronal hyperexcitability and reduce seizure frequency in pilocarpine- and kainate-induced epilepsy models, suggesting its potential therapeutic utility in epilepsy management (Lim et al., 2019) In addition, MCC950, an NLRP3 inflammasome inhibitor, has demonstrated significant neuroprotective effects in animal studies by reducing neuronal damage after status epilepticus (SE) and alleviating depressive-like behaviors, representing a novel avenue for precision anti-inflammatory therapy (Hong et al., 2024)

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Resume FARXIGA when the patient is clinically stable and has resumed oral intake Hypoglycemia: FARXIGA can increase the risk of hypoglycemia when coadministered with insulin and insulin secretagogues

These techniques can establish chemical fingerprint profiles for raw materials and final products, allowing for qualitative identification and quantitative traceability of active metabolites