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doi: 10.1155/2020/6137521

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doi: 10.3389/fphar.2024.1276551 Summary Keywords epilepsy-depression comorbidity, neuroinflammation, gut-brain axis, natural anti-inflammatory agents, aging-related inflammation Citation Shi Y-Q, Yang H-C, He C, Wang Y-H, Zheng J, Wang X-Y, Hao F-Y, Feng C-W, Ma L, Zhang Y-H and Liu Z (2025) Inflammatory links between epilepsy and depression: a review of mechanisms and therapeutic strategies

Autophagy deficiency in neurons results in buildup of ubiquitinated proteins, dystrophy of neural terminals, impairments in synaptic transmission, and eventually, neurodegeneration observed in both neurodegenerative and neurodevelopmental disorders [245, 249, 250]