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However, in AD, there are decreased activities of reductases, leading to increases in the release of MetSO and ROS, thereby worsening the oxidative state

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It is worth noting that this cardioprotective effect of exenatide outweighed the fact that a greater proportion of patients on exenatide treatment possessed CVD risk factors such as prior ischemic heart disease, obesity, hyperlipidemia, and hypertension [98]