Sequential intensification of metformin treatment in type 2 diabetes with liraglutide followed by randomized addition of basal insulin prompted by A1C targets
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More recently, a pooled analysis of four randomized, placebo-controlled trials showed that semaglutide decreased the risk of the combined endpoint of CVD or HF, as well as the risk of worsening HF events in patients with HFpEF [91]
A recent study published in Diabetes Obesity and Metabolism found that individuals using these medications lost significant amounts of fat but also experienced some degree of muscle loss, with lean body mass reductions making up approximately 25%40% of total weight Trusted Source Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies Neeland IJ, Linge J, Birkenfeld AL Go to Source loss
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GLP-1-related hair loss is typically telogen effluvium, triggered by the physiological stress of rapid weight loss and caloric restriction
