Dickkopf-related protein 3 (DKK-3) is a glycoprotein secreted upon tubular injury that promotes scarring that significantly predicts estimated glomerular filtration rate (eGFR) decline and identifies patients at high risk of CKD progression 187
16 Finally, compared to other GLP-1 receptor agonists like dulaglutide, semaglutide is generally more potent, longer-acting, and often leads to greater HbA1c reductions and weight loss
[1] For Wegovy: Unopened pens must be stored in the refrigerator at 36F to 46F (2C to 8C)
However, its also worth noting that poorly managed diabetes can cause nerve damage over time, possibly resulting in muscle aches, numbness, and tingling, Dr
Always consult a licensed healthcare provider before beginning, adjusting, or discontinuing any medication
Hydration needs should be individualized, with caution in those with heart or kidney disease