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Lancet Healthy Longevity 3 , 6777 (2022)

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Clinicians have also noted that sudden caloric deficits can lead the brain to decrease reproductive hormone production as a protective mechanism

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In fact, early life allergen exposure appears to elevate the level of neurotrophins and cause PNEC hyper-innervation and nodose neuron hyperactivity, inducing mucin secretion ( With regards to airway remodeling, TNF- increases the synthesis of BDNF from ASM and enhances the production and deposition of collagen-1, collagen-3, and fibronectin, as well as the activity of MMP-2 and MMP-9 (Freeman et al., 2017), and is involved in muscle cell proliferation (Peng et al., 2005