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Moreover, smooth-fitting curve analysis identified a threshold effect: below 358.7 pg/mL, each 10 pg/mL increase in vitamin B12 was associated with a 4.4% increase in clinical pregnancy rate (OR = 1.04, P = 0.03), beyond which no further benefit was observed

Osuga Y, Harada K, Tsuboi T

At the genus level (Figure S1B), the VPA-ASD group showed marked enrichment of Turicibacter and depletion of beneficial genera such as Bifidobacterium, Akkermansia, and Lactobacillus

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OS can be overcome by reducing generation of ROS or increasing the amounts of antioxidants available

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