(2019) Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic Russian Academy of Sciences transformation by preserving intracellular redox balance, Proc
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Glutathione aids in preventing ferroptosis by neutralizing ROS and sustaining the function of the GPx4 enzyme, thereby protecting cells from lipid peroxidation
Following this step, beads were washed three times with lysis buffer and the co-immunoprecipitates (co-IP) were analyzed by Western blot analysis
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The nature of how impaired glutamate cysteine ligase, the enzyme that naturally produces gamma-glutamylcysteine (GGC), can make cells more susceptible to mutagens due to lower glutathione (GSH) [4, 5] has been well studied