In the Phase 2 trial, nausea ranged from approximately 14% at the 1 mg dose to 60% at the 12 mg dose, with most cases occurring during dose stepping
This classification can limit insurance coverage, forcing some patients to pay out of pocket or abandon treatment altogether
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Compounding may be appropriate when: A required dose, concentration, or formulation is not commercially available An FDA-approved drug is in a temporary shortage A patient has a documented allergy or intolerance to an inactive ingredient Compounding is intended to address medical necessity , not convenience, mass substitution, or price alone
Connecticut Medicine 1995, 59: 263-70
While medications have transformed treatment for many people living with obesity and type 2 diabetes, lifestyle still plays a critical role in metabolic health