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While oral absorption is limited for B12, taking very high doses (e.g., 1000mcg or 2000mcg) can allow for a small amount of passive absorption that doesnt rely on intrinsic factor

Obesity, in turn, is associated with chronic low-grade inflammation

Better sleep further supports metabolic health through improved insulin sensitivity and appetite hormone regulation

May enhance tissue regeneration and recovery at the cellular level

That same pathway, when chronically overactive, is one of the best-documented drivers of cancer growth and spread, to the point that a class of approved cancer drugs exists specifically to block it

While these substances are gaining popularity, it's crucial to recognize the significant risks they pose