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To query whether weight loss by incretin agonism would impact cancer outcomes in pre-clinical models, we studied the impact of medical weight loss on two deadly cancers including pancreatic ductal adenocarcinoma (PDAC) and lung adenocarcinoma (LUAD) as either obesity-associated or obesity-independent cancers, respectively

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Keyster et al

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Mild nausea or GI upset can occur and often fades

1 is a diagram illustrating the presumptive pharmacological effects of administration of a PDE-5 inhibitor and PT-141 according to one embodiment of the invention FIG