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A typical FDA-approved regimen for pernicious anemia includes: 100 g IM/SC daily for 67 days Then every other day for 7 doses Then every 34 days for 23 weeks Followed by 100 g monthly for life Schedule follow-up and monitor progress Potassium levels should be monitored during the first 48 hours of treatment, as rapid red blood cell production may lead to hypokalemia and, rarely, sudden death

The enzyme methionine synthase needs methylcobalamin as a cofactor

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Those with nerve problems might need more B12 to feel better

Symptoms of Vitamin B12 Deficiency While vitamin B12 deficiency is not particularly common in healthy individuals, it is important to recognize the symptoms of B12 deficiency so that you can determine whether supplementation is needed