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Whilst headaches are occasionally reported by users, the evidence suggests they occur infrequently and a clear causal relationship remains uncertain

The study, led by Professor Sachin Kotak from the Indian Institute of Science (IISc)'s Department of Microbiology and Cell Biology, focuses on the protein LIN-5, part of the G/GPR-1/2/LIN-5 complex (analogous to G/LGN/NuMA in humans)

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For the FOXO4-DRI treatment group, 50 M FOXO4-DRI (MCE, HY-P4157) was added to the glucose-free DMEM (Gibco, Catalog #11966-025) medium, followed by 3 h of oxygen-glucose deprivation (OGD) treatment

doi: 10.3389/fmed.2023.1124275