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Proposed by GH-axis researchers to support lean body mass and body-composition changes, though this claim rests on GH and IGF-1's known physiological roles rather than on direct body-composition trials of CJC-1295 itself

PMC 4161975

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Vegans Research shows that vegans are at higher risk of vitamin B12 deficiency and the British Nutrition Foundation recommends they eat fortified foods as well as considering a B12 supplement to make up any shortfall

Mean baseline serum B12 levels were reported in this study but it is not clear what proportion of patients had B12 deficiency

The molecule contains a cysteine-linked disulfide bridge that constrains the peptide into a cyclic conformation, an important feature for maintaining its signaling profile in biochemical and adipocyte-based assays