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KD also produces ketone body carbon which is metabolized to glutamine, the basic precursor of GABA, in addition to the increased consumption of acetate in ketosis, which is converted to glutamine via astrocytes in the brain (97)

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Vazquez-Chantada, M

Gut microbiota dysbiosis in depressed women: the association of symptom severity and microbiota function

Chooklin, S.S

In another study of rats, following a 50 mg/kg dose of luteolin orally or intravenously, luteolin bioavailability was shown to be low, at 4.10%, with a rapid absorption and metabolism rate, large distribution, and high clearance, suggested to be owed to an enterohepatic recirculation [174]