Insufficient maternal nutrition, especially during critical periods of embryonic and fetal development, manifests as an overall elevation of ovarian OS, which, along with impaired mitochondrial antioxidant defenses, may be responsible for these significantly decreased follicle numbers and resultant growth impediment of offspring [275]
Nature 603 , 926933 (2022)
extracted coniferyl ferulate from the roots of Angelica sinensis and demonstrated that the isolated compound is a robust inhibitor of the isozymes of glutathione S-transferase, which, in addition to their other vital functions, contribute to chemoresistance as well as enhance chemosensitivity [205]
Erythrocyte glutathione analyses Erythrocyte glutathione concentration and isotopic enrichment were measured in duplicate 1-mL aliquots of whole blood
Think of them as part of the support crew that makes the real work easier
it should be further investigated, specifically to identify patient populations most likely to benefit from supplementation (173)