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It has long been used in oncology and specific folate-related conditions

However, it is important to note that apoptotic cells can release DAMPs even in the absence of critical plasma membrane perturbations, in particular, via secretory lysosomes or exosomes [234, 235]

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doi: 10.1038/s42003-025-08183-9, 16 ChatterjeeP.PedriniS.DoeckeJ