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Research overwhelmingly describes the safety of GHK-Cu positively, such as when the authors of a 2018 review called it a safe, inexpensive, extensively studied compound.14 However, even though copper peptides have demonstrated an impressive safety track record in studies, there are (as with most skin care actives) a few safety risks to consider

So this is the GHK-Cu Glow Pen, which I started taking back in August

Systematic review (sports medicine) Vasireddi et al

Subcutaneous injections deliver consistently, can be administered on the patients schedule, and dont require a clinic visit each time

If you notice one or more of these, it might mean your antioxidant defenses are running low, and its time to step in