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Case 2 A 46 year-old female, diagnosed with type 2 diabetes and obesity, was referred to us because of having a large local immediate injection site reaction appeared in 15 min following an exenatide BID 5 mcg/20 mcl injection for a month

It is the active ingredient in Novo Nordisk's Wegovy (weight management indication) and Ozempic (diabetes indication)

Training Do resistance training three times per week focused on progressive overload and two sessions of moderate cardio weekly

Often, monotherapy with metformin will not suffice to maintain glucose levels at target

Many Ozempic patients experience severe vomiting, dramatic weight loss, and chronic malnutrition that requires hospitalization for feeding tube placement or total parenteral nutrition

Limited long-term data: most evidence is from animal models, with no long-term human study of NNMT inhibition and oncological endpoints