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Food and Drug Administration (FDA) in 1963 as a prescription medication for acetaminophen (paracetamol) overdose and as a mucolytic agent for respiratory conditions [5][6]

In the following sections, we will examine these issues in greater detail, including the limitations of the existing preclinical data and how current human safety evidenceparticularly for nicotinamide riboside (NR)fits into the broader scientific understanding of NAD+ supplementation

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Br J Clin Pharmacol (2002) 53:52634

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R., Esteban, S., Miralles, A., Tan, D