Anesthesiology 110 , 13641370 (2009)
For example, in order to maintain intracellular redox homeostasis and build a powerful antioxidant defense, cancer cells are typically characterized by high level of antioxidants, especially GSH with a high concentration of 10 mM, which is approximately ten times higher than that in normal cells ( In general, elevated GSH can be observed in many cancers, including lung cancer, ovarian cancer, breast cancer, and head-neck cancer, and this adaptive upregulation of GSH has various effects on tumor advancement, metastasis, and drug resistance (Wong et al., 2016)
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But ROS also play useful roles in the body, including helping regulate cell signaling and, in some cases, contributing to cancer cell death.37 38 That means antioxidants can cut both ways
Neuron 28 , 475484 (2000)
This is an important part of understanding what does urine color mean on a day-to-day basis
