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Women with an MTHFR gene mutation may have a harder time processing folate, which could raise their risk of having a baby with spina bifida or other neural tube complications

Durability: Weight often returns after stopping treatment, especially without lifestyle and coaching support

The practical takeaway remains the same: muscle preservation requires active effort

Park JK, Song M, Dominguez CE, Walter MF, Santanam N, Parthasarathy S, Murphy AA

Bariatric-metabolic surgery versus lifestyle intervention plus best medical care in non-alcoholic steatohepatitis (BRAVES): a multicentre, open-label, randomised trial

The price is too high. Emily Wright, a 38-year-old teacher from Toronto, said she vomits so frequently that she had to take a leave of absence from her job