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Unlike the controls, patients with Wilson disease showed significantly increased plasma levels of T helper (Th) 1 cytokines (IL-2, TNF-, and TNF-), Th2 cytokines (IL-5, IL-10, and IL-13), and Th17 cytokines (IL-23)

(2021) further confirmed the implication of necroptosis in CP-induced AKI where pharmacological inhibition of RIPK1/RIPK3/MLKL axis by protocatechuic aldehyde and 6-shogaol, respectively significantly attenuates renal injury