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Specifically, TM6ECL3 is clasped by TM5 and TM7 and stabilized by hydrophobic interactions with TM3, TM5 and ECL2 via L349 6.48b , V352 6.51b , V355 6.54b , P359 6.58b and V360 6.59b , and by polar contacts with TM1, TM3 and TM7 via E354 6.53b , F357 6.56b , E363 ECL3 , Q364 ECL3 and A365 ECL3
If the concentration of Pb and Cd affects the activity of GPx, this can interfere with its antioxidant action, increasing the risk of protein oxidation by ROS
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Auf Protein achten Proteinreiche Ernhrung schtzt die Muskelmasse bei der Gewichtsabnahme und untersttzt die Vertrglichkeit
In macrophages, silence of the SLC7A11 gene promotes iron overload-induced ferroptosis, suggesting that the TGF signaling pathway is crucial for regulating macrophage ferroptosis (80, 81)
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