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Stem cells do their work through the exosomes that they create, so one way to try to get the results of stem cells without using the stem cells themselves is to make use of stem cell exosomes

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In the case of a leaky epithelial barrier, commensals and opportunistic pathogens migrate below the epithelial cell layer

Besides, activation of IKK, a component of IKK complex, can also directly phosphorylate IRS-1 serine to interfere its activation