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Follow the product SmPC titration schedule to minimise these effects

In PD, along with -synuclein accumulation, there is associated inflammation, synaptic dysfunction, dopaminergic neuronal loss, and some data to suggest insulin resistance

Patients pursuing microdosing, where sub-standard doses are titrated to individual tolerance and response

Getting Around An Array of Side Effects While GLP-1 holds promise as a weight loss aid, addressing potential side effects is vital

The primary mechanism of action of these drugs in the treatment of vitiligo is calcineurin inhibition, which causes the transcription of several proinflammatory cytokines essential to the pathophysiology of the early immune response to be disrupted and antigen-specific T-cell reactivity to be downregulated 26

Results are expected in 2026