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Mild side effects of Mounjaro usually go away as the body gets used to the drug

The broader systematic review of GLP-1 drugs in pain conditions [9] and the 2025 comprehensive review in the Journal of Headache and Pain [1] both conclude that the mechanistic case is plausible and interesting, but that human clinical trials with pain as the primary outcome are needed before we can make firm recommendations

Recent clinical research involving over 17,000 adults showed that these medications can lead to a 20% reduction in major adverse cardiovascular events, such as heart attacks and strokes

Compounded versions might cost less but come with different considerations