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Yao et al., 2007

The rate-limiting step in the de novo synthesis of the GSH is catalyzed by gamma-glutamyl-cysteine synthetase (also known as glutamine-cysteine ligase), which is a target gene of Nrf2

If you have an underlying cardiovascular condition

Pompella et al, 2003 describe a number of signalling cascades affected by protein S-glutathionylation: NF-kB/p50 (Pineda-Molina et al., 2001) and PTP1B phosphatase (Barrett et al., 1999), for example, which are able to affect cell proliferation

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