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Paradoxically, while most cancers demonstrate elevated intracellular polyamines correlating with proliferative metabolism, prostate cancer exhibits an inverse polyamine profile, warranting further mechanistic investigation

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Other SSRIs, including citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), and sertraline (Zoloft), have variable effects on weight, and some do not show weight gain until after six months of use

They interact with neurexins (NRXNs) on the presynaptic cell surface to regulate synaptic differentiation, thereby contributing to the formation of either inhibitory or excitatory synapses (81)

There is very little blood-flow to this tissue in the body