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doi: 10.3389/fphar.2023.1142001 Received 11 January 2023 Accepted 06 March 2023 Published 15 March 2023 Volume 14 - 2023 Edited by Xiaoxin Wang, Georgetown University Medical Center, United States Reviewed by Anil Bhanudas Gaikwad, Birla Institute of Technology and Science, India Komuraiah Myakala, Georgetown University, United States Updates Copyright 2023 Huang, Liang and Zhou

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Addition of a large quantity of the enzyme would have increased the enzymatic contribution of the total rate of reaction mixture but that would have made the rate too fast to measure accurately and conveniently, especially at high MBB concentration

This suggests novel therapeutic targets for CKD or heart failure through this kidney-brain neural circuit

In contrast, in the same group of patients, increased expression of TXNIP was connected to a favorable prognosis with normal T cell phenotype

Depending on the location, depth of invasion, and degree of scarring and inflammation, versatile techniques are applicable