Evidence ledger: what does the research actually show
To overcome this limitation, research efforts have been devoted to the development of therapeutic agents with biological mechanisms of action that are independent of the oxygen concentration
It has been shown to influence fibroblast gene expression, collagen synthesis, antioxidant signalling, angiogenic pathway activation, and inflammatory cytokine modulation
Although safe in moderation, potential carnitine side effects include stomach pain, nausea, vomiting and diarrhea
NIOSH/CDC fact sheets and study materials (large cohort studies / ongoing surveillance)
We propose that if the ferroptosis signaling in aged neurons is reduced to an optimal level (by ferroptosis inhibitors or GPX overexpression), axonal fusion can be enhanced in aged neurons, while reducing axonal debris