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Nature 394 , 588592 (1998)

TB-500 is a 43-residue acetylated polypeptide tracking the human Thymosin Beta-4 sequence, studied for G-actin sequestering activity and cytoskeletal remodelling in wound-healing assays

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This nuclear presence of FOXO4 seems to be involved in maintaining the viability of senescent cells by possibly modulating downstream senescence-associated pathways, detailed by changes in p53, Ser15-phospho-p53, and p21 protein levels

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