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[1] Those are some wild doses, but they did lead to incredibly increased serum carnitine concentrations: a 60-78% lift

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Rummel NG, Chaiswing L, Bondada S, St Clair DK, Butterfield DA (2021) Chemotherapy-induced cognitive impairment: focus on the intersection of oxidative stress and TNF

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They found that renal dysfunction might be one of the factors associated with high plasma TMAO concentration and poor prognosis in patients with HF

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