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H2-receptor antagonists (such as famotidine) similarly reduce gastric acid and may impair B12 absorption, though typically to a lesser extent than PPIs

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This is the most common route for B12 in a clinic, usually into the deltoid muscle of the upper arm

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Being awake allows the patient to be moved into the ideal position during treatment, which increases safety and the quality of the result sometimes we will even stand a patient up during a procedure to see how the treatment area looks