Neurology (2015) 85(2):17789
First, most clinical investigations rely on cross-sectional designs, which preclude causal inference and make it unclear whether elevated NETs drive PCOS-related metabolic and reproductive disturbances or merely reflect them
[13] [14] Deficiency impairs these pathways, leading to fatigue and reduced stamina One-carbon metabolism : B12 supports methylation reactions that contribute to various biochemical processes throughout the body Myelin formation : B12 supports the maintenance of myelin sheaths surrounding nerve fibres, ensuring efficient nerve signal transmission Red blood cell production : Adequate B12 is necessary for erythropoiesis
While long-term exposure increases the risk of lung diseases such as chronic obstructive pulmonary disease (COPD) and asthma, especially in adolescents, short-term exposure can cause airway inflammation, hyperreactivity, decreased pulmonary function, susceptibility to microbial infection, and exacerbation of existing lung diseases
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